Article
Thymic modulation of IL-2 and IL-4 synthesis by peripheral T cells.
Cellular immunology - 1 Jul 1991
Wiedmeier S E, Araneo B A, Huang K, Daynes R A
Abstract excerpt
In this paper we provide several lines of evidence to support the hypothesis that the thymus can exert regulatory influences on the functional capabilities of mature recirculating T cells. Our studies demonstrate that while the IL-2-producing potential of T cells that repopulate the secondary lymphoid organs of lethally irradiated and stem cell-reconstituted mice is significantly reduced compared to that of T...
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