Article
Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. III. Analysis of regulatory cells suppressing the induction of thyroiditis.
International immunology - 1 Jan 1990
Sugihara S, Maruo S, Tsujimura T, Tarutani O, Kohno Y, Hamaoka T, Fujiwara H
Abstract excerpt
It has previously been demonstrated that T cell clones with potentials to induce autoimmune thyroiditis exist in lymphoid organs from normal healthy individuals. The present study investigates the nature of regulatory cells co-existing in a normal lymphoid cell population to prevent the activation of these thyroiditis-inducing T cells. T cell-depleted (C57BL/6 x C3H/He) F1 mice (B cell mice) were prepared by...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Female
- Immune Tolerance
- Immunization, Passive
- Lymphocyte Activation
- Lymphocyte Depletion
- Mice
- Phenotype
- T-Lymphocyte Subsets