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Article

EZH2: an epigenetic gatekeeper promoting lymphomagenesis.

Cancer cell - 13 May 2013

Heyn Holger, Esteller Manel

Abstract excerpt

In this issue of Cancer Cell, Béguelin and colleagues highlight EZH2 as an essential regulator for B cell activation and report an addiction of germinal center-derived neoplasms to EZH2 activity. This reversible process is specifically targetable and hence presents high translational value for ly...

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Share to B-Lymphocytes
Share to Cell Transformation, Neoplastic
Share to Enhancer of Zeste Homolog 2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23680141
DOI: 10.1016/j.ccr.2013.04.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23680141-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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EZH2: an epigenetic gatekeeper promoting lymphomagenesis.PMID 23680141Read ↗

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Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of Diffuse Large B Cell LymphomaSemantic proximity Read ↗

Epigenetics of Indolent Lymphoma and How It Drives Novel Therapeutic Approaches-Focus on EZH2-Targeted Drugs.Semantic proximity Read ↗

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