Article
Azole resistance in a clinical isolate of Aspergillus fumigatus from Chile.
Revista iberoamericana de micologia - 1 Jan 2000
Álvarez Duarte Eduardo, Cepeda Nicolás, Miranda Jean
Abstract excerpt
BACKGROUND: Aspergillus fumigatus is a ubiquitous opportunistic pathogen. This fungus can acquire resistance to azole antifungals due to different mutations in the cyp51A gene. Azole resistance has been observed in several continents and appears to be a globally distributed phenomenon. Specific mutations in cyp51A that lead to azole resistance, such as the TR34/L98H modification, have been reported. AIMS: To...
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