Article
Transcriptional expression of selected genes associated with excretion of carboxylic acids from aci mutants of Saccharomyces cerevisiae.
Postepy higieny i medycyny doswiadczalnej (Online) - 29 Apr 2013
Boniewska-Bernacka Ewa, Wieczorek Maciej, Sadakierska-Chudy Anna, Dobosz Tadeusz, Krop-Watorek Anna
Abstract excerpt
INTRODUCTION: Saccharomyces cerevisiae is an excellent model organism for studies of transcriptional regulation of metabolic processes in other eukaryotic cells including human cells. Cellular acid-base balance can be disturbed in pathologic situations such as renal acidosis or cancer. The extracellular pH of malignant solid tumors is acidic in the range of 6.5-6.9. EG07 and EG37 aci mutants of Saccharomyces...
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