Article
Fast and reliable prediction of domain-peptide binding affinity using coarse-grained structure models.
Bio Systems - 1 Jul 2013
Tian Feifei, Tan Rui, Guo Tailin, Zhou Peng, Yang Li
Abstract excerpt
Domain-peptide recognition and interaction are fundamentally important for eukaryotic signaling and regulatory networks. It is thus essential to quantitatively infer the binding stability and specificity of such interaction based upon large-scale but low-accurate complex structure models which could be readily obtained from sophisticated molecular modeling procedure. In the present study, a new method is...
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