Article
Advances in blood pressure genomics.
Circulation research - 10 May 2013
Munroe Patricia B, Barnes Michael R, Caulfield Mark J
Abstract excerpt
The elucidation of genes implicated in Mendelian forms of hypertension demonstrates rare variants with substantial effects are responsible, and often these genes lie within pathways managing sodium homeostasis. More recently with advances in affordable high-throughput genotyping strategies, multiple common genetic variants with modest effects on blood pressure (<1 mmHg systolic) have been discovered in the...
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