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Article

Polymorphisms of the SIPA1 gene and sporadic breast cancer susceptibility.

BMC cancer - 18 Sept 2009

Hsieh Szu-Min, Smith Robert A, Lintell Nicholas A, Hunter Kent W, Griffiths Lyn R

Abstract excerpt

BACKGROUND: The novel breast cancer metastasis modulator gene signal-induced proliferation-associated 1 (Sipa1) underlies the breast cancer metastasis efficiency modifier locus Mtes 1 and has been shown to influence mammary tumour metastatic efficiency in the mouse, with an ectopically expressing Sipa1 cell line developing 1.5 to 2 fold more surface pulmonary metastases. Sipa1 encodes a mitogen-inducible GTPase...

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Source

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Identifiers

PMID: 19765277
DOI: 10.1186/1471-2407-9-331
PMCID: PMC2751777

Genes

SIPA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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