Article
The ongoing conundrum of MLL-AF4 driven leukemogenesis
9 May 2013
Abstract excerpt
In this issue of Blood, Bueno and colleagues explore the developmental impact, as well as the transforming capacity, of the mixed-lineage leukemia (MLL)–AF4 fusion protein in combination with activation of FMS-like tyrosine receptor 3 (FLT3) in human embryonic stem cells (hESCs).1
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