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Article

SOX9 directly regulates <i>IGFBP-4</i> in the intestinal epithelium

10 May 2013

Abstract excerpt

SOX9 regulates cell lineage specification by directly regulating target genes in a discrete number of tissues, and previous reports have shown cell proliferative and suppressive roles for SOX9. Although SOX9 is expressed in colorectal cancer, only a few direct targets have been identified in intestinal epithelial cells. We previously demonstrated increased proliferation in Sox9-deficient crypts through...

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PMID: 23660500
DOI: 10.1152/ajpgi.00086.2013

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