Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular dynamics study of carbohydrate binding module mutants of fungal cellobiohydrolases.

Carbohydrate research - 7 Jun 2013

Shiiba Hirohide, Hayashi Sachio, Yui Toshifumi

Abstract excerpt

The present study reports the systematic survey of binding free energies at the interface between a carbohydrate-binding module (CBM) and a cellulose Iα crystal model using molecular dynamics' calculations. The two wild type CBMs (Cel7A CBM and Cel6A CBM) have been studied, as well as seven mutants of Cel7A CBM. A comparison of the experimental data for the two wild type and the four mutants CBMs (i.e., Y5A, Y5W,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Carbohydrates
Share to Crystallography, X-Ray

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Molecular

Share to Molecular Dynamics Simulation

Share to Mutation

Share to Trichoderma

Source

Identifiers

PMID: 23660003
DOI: 10.1016/j.carres.2013.04.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular dynamics study of carbohydrate binding module mutants of fungal cellobiohydrolases.PMID 23660003Read ↗

The impact of Trichoderma reesei Cel7A carbohydrate binding domain mutations on its binding to a cellulose surface: a molecular dynamics free energy study.Semantic proximity Read ↗

Identification of amino acids responsible for processivity in a Family 1 carbohydrate-binding module from a fungal cellulase.Semantic proximity Read ↗

A Novel Carbohydrate-binding Module from Sugar Cane Soil Metagenome Featuring Unique Structural and Carbohydrate Affinity Properties.Semantic proximity Read ↗

Free Energy Diagram for the Heterogeneous Enzymatic Hydrolysis of Glycosidic Bonds in Cellulose.Semantic proximity Read ↗

Molecular Dynamics Simulations of Family 7 Cellobiohydrolase Mutants Aimed at Reducing Product Inhibition.Semantic proximity Read ↗

Recognition of cello-oligosaccharides by a family 17 carbohydrate-binding module: an X-ray crystallographic, thermodynamic and mutagenic study.Semantic proximity Read ↗

Structural Insight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module.Semantic proximity Read ↗

A theoretical study on binding and stabilization of galactose and novel galactose analogues to the human α-galactosidase A variant causing Fabry disease.Semantic proximity Read ↗

Functional analysis of hyperthermophilic endocellulase from Pyrococcus horikoshii by crystallographic snapshots.Semantic proximity Read ↗

Importance of hydrophobic and polar residues in ligand binding in the family 15 carbohydrate-binding module from Cellvibrio japonicus Xyn10C.Semantic proximity Read ↗

Rational engineering of Cel5E from Clostridium thermocellum to improve its thermal stability and catalytic activity.Semantic proximity Read ↗

Probing the mechanism of cellulosome attachment to the Clostridium thermocellum cell surface: computer simulation of the Type II cohesin-dockerin complex and its variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.