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Article

Male-Female Differences in Upregulation of Vasoconstrictor Responses in Human Cerebral Arteries

29 Apr 2013

Abstract excerpt

BACKGROUND AND PURPOSE: Male-female differences may significantly impact stroke prevention and treatment in men and women, however underlying mechanisms for sexual dimorphism in stroke are not understood. We previously found in males that cerebral ischemia upregulates contractile receptors in cerebral arteries, which is associated with lower blood flow. The present study investigates if cerebral arteries from men...

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PMID: 23658641
DOI: 10.1371/journal.pone.0062698

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