Article
Cerebral vasoconstriction after subarachnoid hemorrhage--role of changes in vascular receptor phenotype.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2008
Hansen-Schwartz Jacob, Ansar Saema, Edvinsson Lars
Abstract excerpt
The pathological constriction of cerebral arteries known as cerebral vasospasm (CVS) is with a delay of 4 to 10 days linked to subarachnoid hemorrhage. Several agents have been suggested as being responsible; amongst these perhaps 5-hydroxytryptamine (5-HT) and endothelin-1 (ET-1) are the most prominent given their ability to elicit powerful constriction of cerebral arteries. Investigating both 5-HT and ET...
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