Article
Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens).
Infection and immunity - 1 Feb 1997
Ramakrishnan L, Valdivia R H, McKerrow J H, Falkow S
Abstract excerpt
Mycobacterium marinum grows at an optimal temperature of 33 degrees C, far lower than that for M. tuberculosis. Consequently, M. marinum infection of mammals is restricted largely to the cooler surfaces of the body, such as the extremities, but it causes a systemic infection in a large number of poikilothermic animals. Here, we describe a laboratory animal model for M. marinum disease in the leopard frog (Rana...
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