Article
A rapid membrane potential assay to monitor CFTR function and inhibition.
Journal of biomolecular screening - 1 Oct 2013
Maitra Rangan, Sivashanmugam Perumal, Warner Keith
Abstract excerpt
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is an important regulator of ion transport and fluid secretion in humans. Mutations to CFTR cause cystic fibrosis, which is a common recessive genetic disorder in Caucasians. Involvement of CFTR has been noted in other importa...
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