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Article

Prolactin receptor gene polymorphisms are associated with gestational diabetes.

Genetic testing and molecular biomarkers - 1 Jul 2013

Le Trang N, Elsea Sarah H, Romero Roberto, Chaiworapongsa Tinnakorn, Francis Gary L

Abstract excerpt

AIMS: Human placental lactogen (hPL) acts via the prolactin receptor (PRLR) on maternal β-cells to mediate increases in β-cell mass and function during normal pregnancy. This interaction between hPL and PRLR is essential to maintain normal glucose homeostasis and to address the increased metabolic demands of pregnancy. Given the importance of the PRLR-hPL axis in pancreatic islet cell adaptation to pregnancy, we...

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Source

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Identifiers

PMID: 23651351
DOI: 10.1089/gtmb.2013.0009
PMCID: PMC3700434

Genes

PRLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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