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FOXM1 / DEPDC1 feedback loop promotes hepatocarcinogenesis and represents promising targets for cancer therapy

14 Jul 2024

Abstract excerpt

Abstract Forkhead box M1 (FOXM1) is a key regulator of mitosis and is identified as an oncogene involved in several kinds of human malignancies. However, how it induces carcinogenesis and related therapeutic approaches remains not fully understood. In this study, we aimed to identify a regulatory axis involving FOXM1 and its target gene DEP domain containing 1 (DEPDC1) and investigate their biological functions....

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PMID: 39004911
DOI: 10.1111/cas.16273

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