Article
A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine lung.
PloS one - 1 Jan 2013
Sun Huanxing, Choo-Wing Rayman, Sureshbabu Angara, Fan Juan, Leng Lin, Yu Shuang, Jiang Dianhua, Noble Paul, Homer Robert J, Bucala Richard, Bhandari Vineet
Abstract excerpt
BACKGROUND: The role and mechanism of action of MIF in hyperoxia-induced acute lung injury (HALI) in the newborn lung are not known. We hypothesized that MIF is a critical regulatory molecule in HALI in the developing lung. METHODOLOGY: We studied newborn wild type (WT), MIF knockout (MIFKO), and...
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