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Article

Regulation of alveolar septation by microRNA-489

31 Dec 2015

Abstract excerpt

MicroRNAs (miRs) are small conserved RNA that regulate gene expression. Bioinformatic analysis of miRNA profiles during mouse lung development indicated a role for multiple miRNA, including miRNA-489. miR-489 increased on completion of alveolar septation [postnatal day 42 (P42)], associated with decreases in its conserved target genes insulin-like growth factor-1 (Igf1) and tenascin C (Tnc). We hypothesized that...

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PMID: 26719145
DOI: 10.1152/ajplung.00145.2015

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