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Article

HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas

30 Apr 2013

Abstract excerpt

High-risk types of human papilloma virus (HPV) are increasingly associated with oropharyngeal squamous cell carcinoma (OPSCC). Strikingly, patients with HPV-positive OPSCC are highly curable with ionizing radiation and have better survival compared with HPV-negative patients, but the underlying molecular mechanisms remain poorly understood. We applied an array-based approach to monitor global changes in CpG...

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Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Head and Neck Cancer Studies

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PMID: 23635773
DOI: 10.1172/jci67010

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