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Article

Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas

5 Apr 2017

Abstract excerpt

BACKGROUND: Head and neck squamous cell carcinomas (HNSCCs) represent a heterogeneous group of cancers for which human papilloma virus (HPV) infection is an emerging risk factor. Previous studies showed promoter hypermethylation in HPV(+) oropharyngeal cancers, but only few consistent target genes have been so far described, and the evidence of a functional impact on gene expression is still limited. METHODS: We...

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Share to Cervical Cancer and HPV Research
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PMID: 28381277
DOI: 10.1186/s13073-017-0419-z

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