Article
Activating mutations and senescence secretome: new insights into HER2 activation, drug sensitivity and metastatic progression.
Breast cancer research : BCR - 23 Apr 2013
Acharyya Swarnali
Abstract excerpt
HER2 amplification and overexpression is observed in approximately 20% of breast cancers and is strongly associated with poor prognosis and therapeutic responsiveness to HER2 targeted agents. A recent study by Bose and colleagues suggests that another subset of breast cancer patients without HER2...
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