Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p95HER2 and Breast Cancer

23 Feb 2011

Abstract excerpt

A subtype of HER2-positive tumors with distinct biological and clinical features expresses a series of carboxy-terminal fragments collectively known as p95HER2. One of these fragments, named 100- to 115-kDa p95HER2 or 611-CTF, is hyperactive because of its ability to form homodimers maintained by intermolecular disulfide bonds. Despite lacking the majority of the extracellular domain, this HER2 fragment drives...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Biosensing Techniques and Applications
Share to HER2/EGFR in Cancer Research
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21343397
DOI: 10.1158/0008-5472.can-10-3795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p95HER2 and Breast CancerPMID 21343397Read ↗

Activating mutations and senescence secretome: new insights into HER2 activation, drug sensitivity and metastatic progression.Semantic proximity Read ↗

A Comprehensive Review of HER2 in Cancer Biology and TherapeuticsSemantic proximity Read ↗

HER2 in solid tumors: more than 10 years under the microscope; where are we now?Semantic proximity Read ↗

A Comprehensive Review of HER2 in Cancer Biology and TherapeuticsSemantic proximity Read ↗

HER2: Biology, Detection, and Clinical ImplicationsSemantic proximity Read ↗

A Naturally Occurring HER2 Carboxy-Terminal Fragment Promotes Mammary Tumor Growth and MetastasisSemantic proximity Read ↗

Humanized CAR T cells targeting p95HER2Semantic proximity Read ↗

A review of HER2 overexpression and somatic mutations in cancers.Semantic proximity Read ↗

Mammary Tumor Formation and Metastasis Evoked by a HER2 Splice VariantSemantic proximity Read ↗

The human epidermal growth factor receptor 2 (HER2)Semantic proximity Read ↗

The Distinctive Nature of HER2-Positive Breast CancersSemantic proximity Read ↗

The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.