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Clinical implications of the molecular genetics of chronic lymphocytic leukemia

30 Apr 2013

Abstract excerpt

Genetics and molecular genetics have contributed to clarify the biological bases of the clinical heterogeneity of chronic lymphocytic leukemia. In recent years, our knowledge of the molecular genetics of chronic lymphocytic leukemia has significantly broadened, offering potential new clinical implications. Mutations of TP53 and ATM add prognostic information independently of fluorescence in situ hybridization...

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PMID: 23633543
DOI: 10.3324/haematol.2012.069369

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