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Article

A Genetic Study of Psychosis in Huntington's Disease: Evidence for the Involvement of Glutamate Signaling Pathways.

Journal of Huntington's disease - 1 Jan 2018

Tsuang Debby W, Greenwood Tiffany A, Jayadev Suman, Davis Marie, Shutes-David Andrew, Bird Thomas D

Abstract excerpt

BACKGROUND: Psychotic symptoms of delusions and hallucinations occur in about 5% of persons with Huntington's disease (HD). The mechanisms underlying these occurrences are unknown, but the same symptoms also occur in schizophrenia, and thus genetic risk factors for schizophrenia may be relevant to the development of psychosis in HD. OBJECTIVE: To investigate the possible role of genes associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29480208
DOI: 10.3233/JHD-170277

Genes

CTNNA2
DRD2
ERBB4
GRID2
GRIK4
GRM1
NRG1
PCNT
RELN
SLC1A2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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