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Article

Defects of leukocyte migration in primary immunodeficiencies

30 Apr 2013

Abstract excerpt

This Viewpoint gives an overview of the inherited disorders that are characterized by defects of leukocyte trafficking. Three paradigmatic diseases have been selected: warts, hypogammaglobulinemia, infections, and myelokathexis; Wiskott-Aldrich; and leukocyte adhesion deficiency syndromes. These conditions encompass defects in the steps that are required for leukocyte motility: from the response to chemokines,...

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PMID: 23630104
DOI: 10.1002/eji.201243155

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