Article
Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals.
Antimicrobial agents and chemotherapy - 1 Jul 2013
Eddouzi Jamel, Parker Josie E, Vale-Silva Luis A, Coste Alix, Ischer Françoise, Kelly Steve, Manai Mohamed, Sanglard Dominique
Abstract excerpt
Antifungal resistance of Candida species is a clinical problem in the management of diseases caused by these pathogens. In this study we identified from a collection of 423 clinical samples taken from Tunisian hospitals two clinical Candida species (Candida albicans JEY355 and Candida tropicalis JEY162) with decreased susceptibility to azoles and polyenes. For JEY355, the fluconazole (FLC) MIC was 8 μg/ml. Azole...
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