Article
Antifungal resistance: why are we losing this battle?
Future microbiology - 1 Jan 2024
Paiva Macedo Jamile de, Dias Vanessa Cordeiro
Abstract excerpt
The emergence of fungal pathogens and changes in the epidemiological landscape are prevalent issues in clinical mycology. Reports of resistance to antifungals have been reported. This review aims to evaluate molecular and nonmolecular mechanisms related to antifungal resistance. Mutations in the ERG genes and overexpression of the efflux pump (MDR1, CDR1 and CDR2 genes) were the most reported molecular mechanisms...
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