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Article

A functional variant rs353292 in the flanking region of miR-143/145 contributes to the risk of colorectal cancer.

Scientific reports - 22 Jul 2016

Yuan Fang, Sun Ruifen, Li Lijuan, Jin Bo, Wang Yanyun, Liang Yundan, Che Guanglu, Gao Linbo, Zhang Lin

Abstract excerpt

MicroRNA (miR)-143 and miR-145 have been identified as molecular regulators in cell proliferation, cell growth, clone formation, apoptosis, cell cycle, invasion, and migration. We previously found that rs353292 in the flanking region of miR-143/145 showed a high frequency in patients with colorectal cancer (CRC). To identify whether the rs353292 polymorphism is a risk factor for CRC, we conducted this study with...

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Identifiers

PMID: 27444415
DOI: 10.1038/srep30195
PMCID: PMC4957080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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