Article
Efficacy and toxicity of clioquinol treatment and A-beta42 inoculation in the APP/PSI mouse model of Alzheimer's disease.
Current Alzheimer research - 1 Jun 2013
Zhang Yi-Hong, Raymick James, Sarkar Sumit, Lahiri Debomoy K, Ray Balmiki, Holtzman David, Dumas Melanie, Schmued Larry C
Abstract excerpt
Alzheimer's disease (AD), the most common human neurodegenerative disease, is characterized pathologically by numerous deposits of amyloid plaques in the brain. Systemic administration of clioquinol (CQ) and inoculation with amyloid-beta42 (Aβ42) vaccines have been demonstrated to significantly i...
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