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Article

VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineered mouse model of lung adenocarcinoma.

BMC cancer - 29 Apr 2013

Majeti Bharat K, Lee Joseph H, Simmons Brett H, Shojaei Farbod

Abstract excerpt

BACKGROUND: VEGF is one of the key drivers of physiological or pathological angiogenesis hence several VEGF inhibitors are in different stages of clinical development. To further dissect the role of VEGF in different stages of tumor progression in lung tumors, we utilized KrasG12D-LSL GEMMs (gene...

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Identifiers

PMID: 23627488
DOI: 10.1186/1471-2407-13-213
PMCID: PMC3648493

Genes

KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23627488-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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