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Article

Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis.

Cancer prevention research (Philadelphia, Pa.) - 1 Apr 2009

Gandhi Leena, McNamara Kate L, Li Danan, Borgman Christa L, McDermott Ultan, Brandstetter Kathleyn A, Padera Robert F, Chirieac Lucian R, Settleman Jeffrey E, Wong Kwok-Kin

Abstract excerpt

Non-small cell lung cancer (NSCLC) has a poor prognosis, with substantial mortality rates even among patients diagnosed with early-stage disease. There are few effective measures to block the development or progression of NSCLC. Antiangiogenic drugs represent a new class of agents targeting multiple aspects of tumor progression, including cell proliferation, invasion, migration, and outgrowth of metastatic...

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Identifiers

PMID: 19336729
DOI: 10.1158/1940-6207.CAPR-08-0213
PMCID: PMC2696128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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