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Article

Interleukin 7 and thymic stromal lymphopoietin: from immunity to leukemia.

Cellular and molecular life sciences : CMLS - 1 Feb 2014

Tal Noa, Shochat Chen, Geron Ifat, Bercovich Dani, Izraeli Shai

Abstract excerpt

Cancer is often caused by deregulation of normal developmental processes. Here, we review recent research on the aberrant activation of two hematopoietic cytokine receptors in acute lymphoid leukemias. Somatic events in the genes for thymic stromal lymphopoietin and Interleukin 7 receptors as well as in their downstream JAK kinases result in constitutive ligand-independent activation of survival and proliferation...

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Source

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Identifiers

PMID: 23625073
DOI: 10.1007/s00018-013-1337-x
PMCID: PMC11113825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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