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Article

A support vector machine for identification of single-nucleotide polymorphisms from next-generation sequencing data.

Bioinformatics (Oxford, England) - 1 Jun 2013

O'Fallon Brendan D, Wooderchak-Donahue Whitney, Crockett David K

Abstract excerpt

MOTIVATION: Accurate determination of single-nucleotide polymorphisms (SNPs) from next-generation sequencing data is a significant challenge facing bioinformatics researchers. Most current methods use mechanistic models that assume nucleotides aligning to a given reference position are sampled from a binomial distribution. While such methods are sensitive, they are often unable to discriminate errors resulting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23620357
DOI: 10.1093/bioinformatics/btt172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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