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Article

Error correction and assembly complexity of single molecule sequencing reads

2014-06-18

Abstract excerpt

Third generation single molecule sequencing technology is poised to revolutionize genomics by enabling the sequencing of long, individual molecules of DNA and RNA. These technologies now routinely produce reads exceeding 5,000 basepairs, and can achieve reads as long as 50,000 basepairs. Here we evaluate the limits of single molecule sequencing by assessing the impact of long read sequencing in the assembly of the...

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Literature Corpus work
245a6e4d-f68a-5dda-9e29-3f85f1346b6a
DOI
10.1101/006395
Open publication

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Error correction and assembly complexity of single molecule sequencing readsDOI 10.1101/006395
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