Article
Influence of Two DNA Repair Pathway Polymorphisms in Colorectal Cancer Risk in Southwest Iran.
Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2020
Hosseini Seyed Mohammad, Mohammadiasl Javad, Talaiezadeh Abdulhasan, Alidadi Rahim, Bijanzadeh Mahdi
Abstract excerpt
OBJECTIVE: X-ray cross-complementing group 1 (XRCC1) and 8 Oxo guanine DNA-glycosylase 1 (OGG1) genes are implicated in the repair of single-stranded breaks (SSBRs) and base excision repair (BER) pathways. Common polymorphisms in DNA repair genes are supposed to decrease the capability of DNA repair and cause genetic instability. This study was designed to investigate the association between XRCC1 (rs25487) and...
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