Article
454 sequencing reveals extreme complexity of the class II Major Histocompatibility Complex in the collared flycatcher.
BMC evolutionary biology - 31 Dec 2010
Zagalska-Neubauer Magdalena, Babik Wiesław, Stuglik Michał, Gustafsson Lars, Cichoń Mariusz, Radwan Jacek
Abstract excerpt
BACKGROUND: Because of their functional significance, the Major Histocompatibility Complex (MHC) class I and II genes have been the subject of continuous interest in the fields of ecology, evolution and conservation. In some vertebrate groups MHC consists of multiple loci with similar alleles; therefore, the multiple loci must be genotyped simultaneously. In such complex systems, understanding of the evolutionary...
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