Article
The impact of genetics profile (gene polymorphisms) in obese non-PCOS women entering an IVF/ICSI program.
Current drug targets - 1 Jul 2013
Anagnostou Elli, Drakakis Petros, Marinopoulos Spyridon, Mavrogianni Despina, Loutradis Dimitrios
Abstract excerpt
Data concerning the effects of increased body mass index (BMI) on ovarian and pregnancy outcome are rich, but the results are rather controversial. Regarding pharmacogenetics, gene polymorphisms of hormonal receptor genes, such as Estrogen Receptor alpha (ESR1), Estrogen Receptor beta (ESR2) and FSH receptor (FSHR) genes, are associated with ovarian stimulation and pregnancy outcome and may constitute a useful...
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