Article
Do estrogen receptor alpha polymorphisms have any impact on the outcome in an ART program?
Journal of assisted reproduction and genetics - 1 Apr 2013
Anagnostou Elli, Malamas Fotodotis, Mavrogianni Despina, Dinopoulou Vasiliki, Drakakis Peter, Kallianidis Konstantinos, Loutradis Dimitris
Abstract excerpt
PURPOSE: To investigate two of the most studied estrogen receptor alpha polymorphisms (PvuII and XbaI) in combination, in order to evaluate their impact on an ART program outcome. METHODS: 203 normally ovulating women who underwent IVF or ICSI treatment were genotyped for PvuII and XbaI polymorphisms in ESR1 intron 1 using Real-Time PCR. The relationship between the presence of polymorphic alleles and the...
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