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Article

Quantitative trait loci for interhemispheric commissure development and social behaviors in the BTBR T⁺ tf/J mouse model of autism.

PloS one - 1 Jan 2013

Jones-Davis Dorothy M, Yang Mu, Rider Eric, Osbun Nathan C, da Gente Gilberto J, Li Jiang, Katz Adam M, Weber Michael D, Sen Saunak, Crawley Jacqueline, Sherr Elliott H

Abstract excerpt

BACKGROUND: Autism and Agenesis of the Corpus Callosum (AgCC) are interrelated behavioral and anatomic phenotypes whose genetic etiologies are incompletely understood. We used the BTBR T⁺ tf/J (BTBR) strain, exhibiting fully penetrant AgCC, a diminished hippocampal commissure, and abnormal behaviors that may have face validity to autism, to study the genetic basis of these disorders. METHODS: We generated 410...

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Identifiers

PMID: 23613947
DOI: 10.1371/journal.pone.0061829
PMCID: PMC3626795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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