Article
Formation of functional areas in the cerebral cortex is disrupted in a mouse model of autism spectrum disorder.
Neural development - 3 Apr 2015
Fenlon Laura R, Liu Sha, Gobius Ilan, Kurniawan Nyoman D, Murphy Skyle, Moldrich Randal X, Richards Linda J
Abstract excerpt
BACKGROUND: Autism spectrum disorders (ASD) are a group of poorly understood behavioural disorders, which have increased in prevalence in the past two decades. Animal models offer the opportunity to understand the biological basis of these disorders. Studies comparing different mouse strains have identified the inbred BTBR T + tf/J (BTBR) strain as a mouse model of ASD based on its anti-social and repetitive...
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