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Article

BRAF alterations in pediatric low grade gliomas and mixed neuronal-glial tumors.

Journal of neuro-oncology - 1 Jul 2013

Dimitriadis Efthymios, Alexiou George A, Tsotsou Panagiota, Simeonidi Efthymia, Stefanaki Kalliopi, Patereli Amalia, Prodromou Neofytos, Pandis Nikolaos

Abstract excerpt

Low grade astrocytomas are the most common brain tumor in children. Recent studies have identified alterations in the BRAF serine/threonine kinase gene that result in mitogen activated protein kinase pathway activation. Herewith, we investigated the genetic changes of BRAF in pediatric low grade...

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Source

Identifiers

PMID: 23612919
DOI: 10.1007/s11060-013-1131-5

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23612919-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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