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Article

New strategies in pediatric gliomas: molecular advances in pediatric low-grade gliomas as a model.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2013

Raabe Eric, Kieran Mark W, Cohen Kenneth J

Abstract excerpt

Pediatric low-grade gliomas (pLGG) account for more brain tumors in children than any other histologic subtype. While surgery, chemotherapy and radiation remain the mainstay of upfront treatment, recent advances in molecular interrogation of pLGG have shown a small number of recurring genetic mutations in these tumors that might be exploited therapeutically. Notable findings include abnormalities in the RAS/MAP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-myb

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Source

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Identifiers

PMID: 23881924
DOI: 10.1158/1078-0432.CCR-13-0662
PMCID: PMC4696061

Genes

BRAF
MYB
MYBL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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