Article
Ferromagnetic Resonance Multiplexing of Orthogonal Magnetic Nanoparticle Agglutination for Simultaneous Analysis of Nucleic Acid Mutations and Nonspecific Interactions.
Small (Weinheim an der Bergstrasse, Germany) - 1 Jun 2025
Zhang Xiaoyan, Fang Yuan, Chen Zhenhua, He Yilong, Gao Qian, Dong Zhuxin, Huang Zhongchao, Tian Bo
Abstract excerpt
Developing multiplexed platforms capable of simultaneously analyzing specific biomolecular interactions and nonspecific binding effects in a single reaction system holds significant potential for accurate disease diagnostics. Here, a ferromagnetic resonance (FMR) biosensor is presented that integrates orthogonal magnetic nanoparticle (MNP) agglutination with genetic algorithm (GA)-based spectral deconvolution....
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