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Molecular surveillance of multiplicity of infection, haplotype frequencies, and prevalence in infectious diseases

2025-03-14

Abstract excerpt

<h4>Background</h4> The presence of multiple different pathogen variants within the same infection, referred to as multiplicity of infection (MOI), confounds molecular disease surveillance in diseases such as malaria. Specifically, if molecular/genetic assays yield unphased data, MOI causes ambiguity concerning pathogen haplotypes. Hence, statistical models are required to infer haplotype frequencies and MOI from...

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Literature Corpus work
c5533f28-beaa-5192-b5a2-98fbd4a7ba16
DOI
10.1101/2025.03.13.642971
Open publication

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Molecular surveillance of multiplicity of infection, haplotype frequencies, and prevalence in infectious diseasesDOI 10.1101/2025.03.13.642971
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