Article
Sox10 and Itgb1 interaction in enteric neural crest cell migration.
Developmental biology - 1 Jul 2013
Watanabe Yuli, Broders-Bondon Florence, Baral Viviane, Paul-Gilloteaux Perrine, Pingault Veronique, Dufour Sylvie, Bondurand Nadege
Abstract excerpt
SOX10 involvement in syndromic form of Hirschsprung disease (intestinal aganglionosis, HSCR) in humans as well as developmental defects in animal models highlight the importance of this transcription factor in control of the pool of enteric progenitors and their differentiation. Here, we characterized the role of SOX10 in cell migration and its interactions with β1-integrins. To this end, we crossed the...
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