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Identification of immunological characteristics and cuproptosis-related molecular clusters in primary Sjögren's syndrome

18 Nov 2023

Abstract excerpt

BACKGROUND: Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disease characterized by lymphocyte infiltration of the exocrine glands. The typical clinical symptoms of pSS include dryness of the mouth (xerostomia) and eyes (xerophthalmia), fatigue, and joint pain. Cuproptosis is a recently identified mode of programmed cell death that leads to the progression of multiple diseases, and the precise...

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PMID: 37984252
DOI: 10.1016/j.intimp.2023.111251

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