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Dissecting the mammary gland one cell at a time

20 Jun 2018

Abstract excerpt

Dissecting cellular differentiation hierarchies in the mammary gland is a prerequisite for understanding both normal development and malignant transformation during tumorigenesis and tumor cell-of-origin. To achieve these goals, several recent papers utilized single cell RNA-seq and lineage tracing to improve our understanding of the composition of the mammary epithelium at different developmental stages.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29946144
DOI: 10.1038/s41467-018-04905-2

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