Article
A functional polymorphism at the FGF10 gene is associated with extreme myopia.
Investigative ophthalmology & visual science - 7 May 2013
Hsi Edward, Chen Ku-Chung, Chang Wan-Shu, Yu Ming-Lung, Liang Chung-Ling, Juo Suh-Hang Hank
Abstract excerpt
PURPOSE: Fibroblast growth factor-10 (FGF10) can modulate extracellular matrix associated genes and, therefore, it could be a myopia susceptibility gene. This study used an animal model, single nucleotide polymorphisms (SNPs) association, and genetic functional assay to evaluate FGF10 gene for my...
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