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Article

A functional polymorphism at the FGF10 gene is associated with extreme myopia.

Investigative ophthalmology & visual science - 7 May 2013

Hsi Edward, Chen Ku-Chung, Chang Wan-Shu, Yu Ming-Lung, Liang Chung-Ling, Juo Suh-Hang Hank

Abstract excerpt

PURPOSE: Fibroblast growth factor-10 (FGF10) can modulate extracellular matrix associated genes and, therefore, it could be a myopia susceptibility gene. This study used an animal model, single nucleotide polymorphisms (SNPs) association, and genetic functional assay to evaluate FGF10 gene for myopia. METHODS: The expression levels of FGF10 gene were compared among the form deprivation myopic (FDM) eyes, the...

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Source

Identifiers

PMID: 23599340
DOI: 10.1167/iovs.13-11814

Genes

FGF10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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