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Article

A PAX6 gene polymorphism is associated with genetic predisposition to extreme myopia.

Eye (London, England) - 1 Apr 2008

Tsai Y-Y, Chiang C-C, Lin H-J, Lin J-M, Wan L, Tsai F-J

Abstract excerpt

PURPOSE: The PAX6 gene is a homeobox gene involved in oculogenesis, ocular growth, and form-deprivation myopia. Our aim was to determine whether PAX6polymorphism at position -12 of intron 9 (IVS9-12C to T, rs667773) is associated with high myopia in Chinese Taiwanese. METHODS: This case-control study compared a study group (n=188) with high myopia whose spherical equivalent was greater than -6.0 D with a control...

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Source

Identifiers

PMID: 17948041
DOI: 10.1038/sj.eye.6702982

Genes

PAX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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